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When treatment is titrated toward weight loss rather than glycemic control, average reductions can be much larger, with a trial-level result of 14.9% body weight loss over 68 weeks under a weight-focused escalation protocol
Common side effects reported in clinical trials include nausea, diarrhea, vomiting, constipation, stomach pain, and injection site reactions
The Wegovy Injection: In the landmark STEP 1 clinical trial , patients using the 2.4 mg weekly injection lost an average of 14.9% of their body weight over 68 weeks, vs 2.4% with the placebo group
Overall fat mass percentage is also reduced by supplementation and lean body mass is increased
