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For most Canadians covered by private insurance, the transition to generic semaglutide is expected to occur at the pharmacy level without patient action, with pharmacists dispensing the generic at the next refill unless a physician has specified the brand-name product is medically necessary
Vecchiet et al
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist designed to bind to GLP-1 receptors, which help regulate appetite.[4] Semaglutide was originally developed as a treatment for T2D to improve blood sugar levels, but clinical trials later showed that patients also lost weight while taking it.[4-8] Additional studies support semaglutides effectiveness in promoting weight loss in non-diabetics.[5,8,11] Semaglutide supports weight loss by suppressing appetite, delaying stomach emptying, and stimulating insulin secretion.[4] It is typically used alongside dietary changes and exercise in adults with and without diabetes.[4] All GLP-1 medications require a prescription from a healthcare provider
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