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The relative contribution of GSTP1 to GSH-conjugation of both QIs was highest at GSH-depleted conditions, while in absolute quantities a higher GSTP1-dependent increase of GSH conjugate formation was seen without BSO pre-treatment ( Figure 5 )

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Rhubarb enema decreases circulating trimethylamine N-Oxide level and improves renal fibrosis accompanied with gut microbiota change in chronic kidney disease rats