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: Off Label Pseudophakic patients with glaucoma (Schmidt et al 2010) A 2010 study (Schmidt et al, 2010) concluded that echothiophate may be effective in lowering IOP in patients with advanced glaucoma that have had previous cataract surgery to replace their eye's natural cloudy lens with a clear aritificial intraocular lens (pseudophakic patients), and for whom maximal medical therapy with newer class medications provides insufficient lowering of IOP
Some studies show a skin-lightening benefit as well, due to direct and indirect inhibition of the tyrosinase enzyme and switching from eumelanin to phaeomelanin production
Enzyme solution may be on the wall or inside of the tube cap
No human safety data exists for these populations
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