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Safety Concerns with Obesity Medications Are GLP-1 Medications Truly Risk-Free

It is hoped that this review will convince scientists and clinicians to look past paracellular permeability to other mechanisms by which endotoxin is taken into the body in the hope that interventions can be devised that prevent endotoxin uptake and that mechanistic interpretations of processes that increased paracellular permeability can be made

Neurological symptoms may take longer to resolveoften several weeks to monthsand improvement may be gradual rather than immediate

However, some healthcare providers may consider prescribing both medications together off-label in select patients who have not achieved adequate weight loss with monotherapy