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Under oxidative stress conditions, NRF2 separates from Keap1 and activates the expression of downstream target genes containing antioxidant response elements (ARE), such as iron heavy chain protein (FTH1) and iron light chain protein (FTL), promoting GSH synthesis and regenerating NADPH to exceed ROS production (36, 83)
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While SSRIs generally have fewer side effects than other types of antidepressants, that doesnt make it less dangerous to mix with alcohol or other substances
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Since glutathione also helps recycle Vitamin C, eating citrus fruits, bell peppers, or taking a Vitamin C supplement can enhance the whole process
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