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Healthcare professionals may use it in regulated clinical or institutional settings according to local prescribing rules
This article reviews current evidence, potential mechanisms, and practical guidance for patients and healthcare providers
The authors recommend providing in-depth counselling and possibly slower titration of GLP-1 RAs during initiation in these groups, particularly those who are known to have discontinued metformin previously, in order to decrease discontinuation rates
Semaglutide was approved in 2022 for use alongside lifestyle changes in pediatric patients aged 12 or older with an initial BMI equal to or greater than the 95th percentile for their age and sex
According to Wang, based on significant differences in the pathophysiology and biochemistry of brain tissues, it is possible to divide HIE into three phases, all of which have apoptosis or necrosis of nerve cells as the final outcome of brain damage 135,136
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