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Many Pakistani doctors prescribe Ozempic off-label for: Clinical Evidence The SUSTAIN-1 trial showed: Up to 57 kg weight loss over 30 weeks Better appetite control Improved metabolic markers However: Wegovy (higher-dose semaglutide) is the FDA-approved weight-loss version, not Ozempic

Statements Author contributions DA: Conceptualization, Writing original draft

Wegovy (a higherdose semaglutide) is the licensed weightloss alternative

Its unusual for the FDA to go against the recommendations of the Pharmacy Compounding Advisory Committee (PCAC), but it has happened at least once before

What we can do is look at the separate trial results and see how they stack up