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doi: 10.1093/humrep/dey256 2 ChangSDunaifA
Australias medicines regulator has only approved the drug for the management of type-2 diabetes - but on TikTok, its been touted as a miracle weight-loss solution thats seen a rise in health professionals prescribing the medicine off-label
The clinical picture the alert describes is specific: abnormal liver function tests showing transaminitis with possible raised bilirubin and coagulopathy. In plain terms, the liver enzymes that leak into the blood when liver cells are dying were elevated, the pigment the liver is supposed to clear was building up, and the blood was losing its ability to clot, which is what happens when a liver stops making the proteins that hold clotting together
Some users employ a 5 days on, 2 days off weekly schedule with the non-DAC version to preserve pulsatile release patterns
Tirzepatide decreased numerous measures of appetite or the drive to eat, including things like hunger and food cravings
