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This concept is supported by the reported elevation of CRP and other inflammatory biomarkers, as well as by evidence of inflammatory cells in endomyocardial biopsies of HFpEF patients [11,12,13,14]
We previously examined GLP-1 dispensing and prescribing patterns immediately following the July 2025 CVS formulary change and found that switching from AOM tirzepatide increased more than 16-fold in July, with most patients transitioning to AOM semaglutide
To maximize the benefits of GLP-1s and reduce potential side effects like nausea, vomiting, constipation and muscle loss, Dushay and other experts offer specific advice
Because of this, if an athlete is prescribed a GLP-1, it's important to be aware of the potential for Relative Energy Deficiency in Sport (REDs) due to under-fueling
This typically resolves within 6-12 months as weight stabilizes, and adequate protein and micronutrient intake can minimize the effect
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