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They demonstrated no significant elevations in IGF-1 levels and no significant changes in body composition parameters, but they did show improvements in a couple of muscle strength tests.11 Study three A separate 1997 study was more promising

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This variant alters the 354th amino acid of the protein sequence from glutamic acid (G allele) to glutamine (C allele

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Elevated GH subsequently stimulates IGF-1 production from the liver and peripheral tissues