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Combination of IGF-IR and RAF/MEK/Erk inhibitors may improve the efficacy in cancer therapy
doi: 10.1093/humrep/17.2.426 156 TostiCPinzautiSSantulliPChapronCPetragliaF
The Wald test was used to derive P values and log 2 (fold change)
One group of researchers found that AOM-treated mice have disruptions of occludin, claudin-5, zona occludens-1, and zona occludens-2 protein expression as assessed with western blots
The result is a dramatically extended half-life and increased bioavailability, making it the gold standard for research in cellular proliferation, muscle hypertrophy, and metabolic signaling
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