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First, SFN stands as a exemplary multi-targeted agent whose pleiotropic mechanismsspanning epigenetic regulation, induction of specialized cell death programs, immunomodulation, and CSC targetingprovide a robust foundation for its efficacy against heterogeneous and treatment-resistant malignancies
This demonstrates that FOXO4-DRI selectively targets and eliminates senescent Leydig cells by causing p53 nuclear exclusion and subsequent apoptosis
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365 Large leukotrienes relieve RA via the Nrf2/HO-1/GPX4 pathway
This malfunction consequently results in increased urinary losses of carnitine
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