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Description

Holst JJ, Orskov C, Nielsen OV, Schwartz TW

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further confirmed that GLP-1 exerts a positive chronotropic effect by directly activating GLP-1 receptors expressed in sinoatrial node pacemaker cells

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presented a magnetically targeted nanocarrier loaded with the PPAR agonist 15d-PGJ2-MNPs, which, when administered intravenously, activated PPAR receptors on macrophages around haematomas, attenuated brain damage, and improved sensory and motor functions in mice after ICH (Wang et al., 2023)

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No adjustments for multiple comparisons were made given the exploratory nature of the study

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However, given its higher efficacy, tirzepatide may lead to more substantial long-term weight maintenance outcomes

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