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doi: 10.2337/db06-0565, 123 RavandiB.IspirovaG.SebekM.MehlerP.BarabasiA
Mutant TDP-43 activates M1 microglia and upregulates pro-inflammatory mediators NOX2, TNF-, and IL-1 (Beers et al., 2011
They observed a greater reduction in levels of rheumatoid factor, malondialdehyde and C-reactive protein (10)
Your provider may: Start with a lower dose and increase more gradually Monitor you more frequently for side effects Recommend additional blood work or imaging to track progress Consider alternative medications or non-medication-based weight loss strategies Bottom Line: Safety First GLP-1 medications have helped many people achieve sustainable weight loss and improved metabolic health, but theyre not one-size-fits-all
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