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Overall, this poem carries out a theme of repentance
A key piece of context: levels of both NAD+ and glutathione decline significantly with age
Since we have now shown that the 1st glutathione-interaction site can serve not only as a scaffold site for GSSR substrates but also as an activator site for GSH for the reduction of non-glutathione disulfide substrates, we would like to suggest to preferably use the terms 1st and 2nd glutathione-interaction site (e.g., in combination with the function as a scaffold or activator) to avoid ambiguities in the future
USA 102 , 16491654 (2005)
Notably, circulating levels decline with age, paralleling reduced tissue repair capacity
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