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Under different ferroptosis induction conditions, p53 promotes ferroptosis partly by inhibiting SLC7A11 expression, while p53 deficiency promotes ferroptosis resistance by SLC7A11 upregulation
Nuclear YAP transcriptionally activates VCPIP1, forming a positive feedback loop that reinforces the expression of prosurvival and multidrug resistance genes
Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite production
In pharmaceutical development, roughly 90% of drugs that work in animals fail in human trials
Liposomal glutathione is the most bioavailable oral form
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