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Park JK, Song M, Dominguez CE, Walter MF, Santanam N, Parthasarathy S, Murphy AA
Conducted from March 29, 2021, to May 18, 2023, the trial aimed to investigate the effect of continued treatment with the maximum tolerated dose (ie, 10 or 15 mg) of once-weekly tirzepatide, compared with placebo, on the maintenance of weight reduction following an initial open-label lead-in treatment period in participants with obesity or overweight
These were generally consistent with the known side-effect profile of GLP-1 receptor agonists and were most frequently observed during the dose-escalation phase
At moderate doses, caffeine is one of the most well-supported ergogenic and fat-loss aids in sports nutrition research
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