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Microscopically, transmural hyperemia of the gastrointestinal tract, intestinal mucosa villi reduction, crypt reduction with focal denudation of superficial epithelia, and large bowel dilatation were all inhibited
As discussed in gut health research more broadly, microbiome disruption drives: Intestinal permeability Systemic inflammation Impaired neurotransmitter production Immune dysregulation In the context of long COVID, gut dysfunction may represent both a consequence of the initial infection and an ongoing driver of systemic inflammatory and neurological symptoms
Accessed May 2026
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