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Thyroid C-Cell Tumors: In mice and rats, tirzepatide (the active ingredient in Zepbound and Mounjaro) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

doi: 10.1001/jamainternmed.2023.6663

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If your total protocol is 48 weeks, the four weeks you spend at the starting dose represent less than 10% of the total journey