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Their work on synthetic analogs of -MSH led to the development of Melanotan I, also known as afamelanotide - the first peptide with melanogenesis-promoting properties
This makes it an attractive compound for researchers studying metabolic dysfunction-associated steatotic liver disease, hepatic insulin sensitivity, and lipid oxidation pathways
These findings are promising but have not yet translated into a licensed product
This receptor pathway has over 15 years of safety data from diabetes medications, providing confidence in its long-term profile
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