Many patients use GLP-1 therapy as a structured period 12 to 24 months to reset appetite patterns, establish healthier habits, and reach a weight their body can maintain
Evidence for the influence of CBD on macrophage function is sparser
Rather than being an either-or choice for most patients, metformin often serves as the foundation while a GLP-1 agonist is added if blood sugar targets are not met or if additional cardiovascular, renal, or weight benefits are needed
Note on insurance: For branded GLP-1s, prescriptions may be covered if filled at your pharmacy, depending on the insurance carrier
Paroxetine (probably the biggest weight gainer of the SSRIs), tricyclic antidepressants like amitriptyline, nortriptyline (have a lot of H2 and serotonin receptor antagonism that causes the weight gain and anticholinergic effects), lithium