Funding This study was funded by grants from the National Key R&D Program of China (2017YFC0908500, 2017YFC1309003), the National Natural Science Foundation of China (81425018, 81672868, 81802775, 82073003, 82002852, 82003267), China Postdoctoral Science Foundation (2019M663252), the Sci-Tech Project Foundation of Guangzhou City (201707020039), the Sun Yat-sen University Clinical Research 5010 Program (2019023), the Special Support Plan of Guangdong Province (No
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doi: 10.1038/cdd.2017.159 17 GuizeRLiuVMRosebrockDJourdainAAHernndez-SnchezMMartinez ZuritaAet al
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The immunogenicity of the RBD may be enhanced by presenting multiple copies of the RBD on a single particle to B cells, allowing multiple antigen-BCR engagements