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Last reviewed: June 22, 2026 Last updated: June 22, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Vitamins B6, B9, and B12 may also be able to prevent migraine episodes or reduce their severity, although the research is limited

Other causes include a genetic predisposition, a high number of pigmented nevi, and a fair complexion (223, 224)

ARE THERE ANY SIDE EFFECTS TO B12 INJECTIONS

Keep supplemental vitamin B6 intake at or below 10 mg per day unless medically supervised