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Lose an average of 22.5% of your body weight in 72 weeks (1 year, 5 months) 1 Lose an average of 20.7% of your body weight in 72 weeks (1 year, 5 months) 2 Lose an average of 16.6% of your body weight in 64 weeks (1 year, 3 months) 3 Lose an average of 10% body weight with oral capsules for weight management 4 1 SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg)
Enzymatic cleavage of albumin results in less efficient FcRn-mediated rescue from lysosomal degradation and, consequently, a dramatically shorter plasma half-life of 3.5 days in humans 60
Doctors prescribe GLP-1 medications to be taken over the long term
Researchers should study its binding sites and conformational changes in depth to provide theoretical support for the design of highly selective drugs
Yang, Z
