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Avoiding Severe Constipation While Taking GLP-1s GLP-1s slow gastric emptying and can cause constipation in some people
Abstract Middle age represents a critical window for metabolic and cognitive health, particularly in the context of rising obesity and diabetes rates
This study, published in the New England Journal of Medicine (2016), showed that semaglutide reduced the risk of major adverse cardiovascular events compared to placebo, suggesting potential cardiovascular benefits rather than harm
In a phase 1b trial, 20 weeks of cagrilintide 2.4 mg once weekly in combination with semaglutide 2.4 mg once weekly (cagrisema) resulted in up to 17.1% WL compared to 9.5% WL with semaglutide 2.4 mg plus placebo in people with obesity [88]
It uses a clever dual activation technique: directly boosting the GLP-1 pathway while optimizing your gut microbiome to produce more of those helpful SCFAs
