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For those who did discontinue, the majority did so during the peak side effect period in weeks six to eight

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After the discovery of SOD as the first line of defense against ROS ( Figure 2 Apart from the SOD and catalase system, the glutathione system, which is composed of glutathione (GSH), -glutamyl cysteine synthase (GCS), GSH synthetase, glutathione peroxidase, and glutathione reductase (GSR), also plays an important role in mediating cellular redox homeostasis

Cells (2019) 8(2):89

Research has indicated that when iron ions are present at specific concentrations, they can inhibit the activity of Runt-related transcription factor 2 (Runx2), a critical regulator of osteoblast differentiation ( Figure 2 )