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Despite the clear target and rapid efficacy of Western clinical antidepressant drugs, they also have the disadvantages of low efficiency, single pathway, and serious adverse effects
For instance, the release of damage-associated molecular patterns (DAMPs) such as HMGB1 during ferroptosis activates receptors like AGER/RAGE, stimulating the NF-B pathway (Wen et al., 2019)
After years of brutal price erosion that decimated returns for Indian exporters, the US generics market has found a floor
Replacement of Sec46 by a cysteine or mutation of any of the 3 other amino acids of the catalytic site results in an abrogation or a diminution of GPX4 enzymatic activity [1]
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