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Liraglutide is additionally approved for the treatment of obesity, at a dose of 3.0 mg (128), while semaglutide is in clinical development as a treatment for obesity (phase 3) and NASH (phase 2)
GLP-1 agonists arent suitable for children under age 12, and those approved for the treatment of type 2 diabetes are not intended for those without type 2 diabetes
The insurer had spent over $300 million on GLP-1 medications, with projections showing costs approaching $1 billion by 2026 if trends continued
The article attributes it to estrogen decline, which reduces insulin sensitivity, slows resting metabolic rate, and shifts fat distribution toward the abdomen
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