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BMC Biol

All these changes lead to cytokine storm characterized by increased expression and release of proinflammatory cytokines that participate in the pathogenesis of ARDS during virus respiratory infections like COVID-19

ROS may be important mediators of cellular injury during COVID-19 sepsis (Silvagno et al., 2020), either following macromolecular damage or by hindering extracellular and intracellular regulatory processes

Slow-wave sleep represents the stage associated with maximal restorative neural processes and synchronized cortical oscillations