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To be eligible, patients must: be aged 18 years or older participate in clinically appropriate lifestyle modifications consistent with the FDA-approved label for their prescribed medication satisfy the criteria for one of the following three categories Starting BMI 27 and 1+ of the following Pre-diabetes (defined by ADA guidelines) Previous MI Previous stroke Symptomatic PAD Starting BMI 30 and 1+ of the following HFpEF Uncontrolled HTN CKD stage 3a or above Starting BMI 35 Scroll down to see Wegovy Indications and Important Safety Information
Unless you have good health reasons requiring weight loss support, it is unlikely that you will be referred for medication with a BMI under 35
Tirzepatide (Mounjaro, Zepbound) is an FDA-approved dual GIP/GLP-1 receptor agonist used for type 2 diabetes and chronic weight management
Echocardiography is also used to determine the left ventricular ejection fraction (LVEF), an objective measure of the heart's pumping ability
Within skeletal muscle, oxidative stress inflicts damage upon mitochondrial DNA, proteins, and lipids, thereby undermining mitochondrial respiration and adenosine triphosphate (ATP) synthesis (83)
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