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Glutathione functions as a tripeptide antioxidant synthesised in the liver, scavenging reactive oxygen species and supporting Phase II detoxification enzymes
Similar content being viewed by others Introduction Fundamental cellular processes, including the electron transport chain (ETC) in the mitochondria and protein folding in the ER, produce reactive oxygen species (ROS) 1
To confirm that weight loss in the setting of cysteine deficiency is due to the concurrent induction of the ISR and OSR, we fed mice a no-Trp diet while administering l-buthionine sulfoximine (BSO), a specific inhibitor of -glutamyl cysteine synthase, which decreases GSH but not cysteine (Fig
The genera in bold are the bacterial TMA producers
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