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Glutathione is naturally produced by the body, but depletes as we age, especially after the age of 45

The p53 protein itself acts as an intrinsic regulator within the cell, primarily tasked with overseeing the cell cycle's progression, including the initiation of cell death

Multiple studies confirm the mechanism in both cell culture and animal models

The incorporation of periodontal biomarkers into established CVD risk estimates, such as those derived from the Framingham Risk Score or pooled cohort equations, would enhance predictive value, particularly among individuals at intermediate risk, where current estimates for 10-year CVD events or other serious complications are shown to be deficient [2]

McGeer, P