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5-Alpha Reductase Inhibitors (Finasteride, Dutasteride) and TRT - Essential context on how true DHT blockers work, their side effect profile, and how they interact with testosterone therapy
Some cardiovascular outcome trials, such as the LEADER trial with liraglutide and the SUSTAIN-6 trial with semaglutide, included fracture events as safety endpoints
Overall, the findings provide cautious, low-certainty reassurance regarding inadvertent maternal exposure, particularly during early pregnancy, but do not establish that these drugs are safe for routine use throughout pregnancy
This means people start at the lowest dose and its increased over time to keep side effects to a minimum
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