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These findings emphasize that targeted antagonism of NMDA receptor signalling lowers body weight independently of MC4R, indicating that this preclinical drug candidate might not only be effective in treating polygenic obesity but also holds potential as an effective weight loss strategy for patients with loss-of-function mutations in MC4R , the most common form of monogenic obesity 32
Its medical use is experimental or off-label
This phospholipid bilayer (a double layer of fats) acts as a protective shield, encasing the glutathione and allowing it to pass safely through the harsh environment of the stomach
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