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Kanayama M, Hayashida M, Hashioka S, Miyaoka T, Inagaki M
Untreated GD sufferers were shown to have much more DNA damage than patients with toxic nodular goitre and healthy people ( 5.2.3 Thyroid cancer Increased production of ROS has been shown to favour cancer development ( According to an analysis of the redox balance, sera antioxidant levels were lower in thyroid cancer patients than in healthy controls, and OxS marker sera levels in thyroid cancer patients were significantly higher than in the control samples ( A disturbed balance between serum OxS and antioxidant defence system markers is typically encountered in thyroid cancer patients compared to healthy individuals ( In PTC and anaplastic thyroid carcinoma, somatic KEAP1 and NFE2L2 mutations activating the Nrf2 pathway were discovered ( 6 Nutrition and OxS Proper nutritional intake is mandatory for overall well-being and better human health
November 2, 2023
J Biol Chem 2000;275:35215-23
