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Genetic experiments using mice lacking the IFN-I receptor, along with Chac2-deficient HL60 cells, showed that disrupting IFN-I signaling prevented Chac2 activation, GSH metabolic reprogramming, and N1 polarization

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Bacteriostatic Water for Injection, USP is: chemically designated H2O and is a sterile, non-pyrogenic preparation of water containing 0.9% (9mg/mL) of benzyl alcohol added as a preservative and has a pH of 5.7 (4.5 - 7.0)

Measurement of GSH/GSSG level For GSH/GSSG level, 143B cells were plated in 12-well plates