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Compared to sitagliptin, GLP-1 analogues are more effective in reducing HbA1C (weight mean difference 0.41%, 95% CI 0.51 to 0.31) and body weight (weight mean difference 1.55 kg, 95% CI 1.98 to 1.12)
It acts as a cell protector, found in most cells, and functions as a potent antioxidant, bolstering the activity of vitamins C and E
The American Society for Metabolic and Bariatric Surgery also reports that weight loss surgery can potentially treat other conditions associated with obesity, including diabetes, heart disease, high blood pressure, joint pain, sleep apnea, and arthritis, and reduce the risk of cancer
Long-term side risks could consist of the body generating antibodies against the drug, which could reduce its efficacy or cause new side effects
