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Adding GLP-1-induced muscle loss on top of natural age-related decline pushes vulnerable patients closer to functional thresholds below which independence becomes compromised

Exercise and activity Exercise is not required for weight loss on tirzepatide, but it dramatically improves body composition outcomes

Runners who previously completed 1820 mile efforts comfortably report hitting severe fatigue at mile 1416, accompanied by cognitive fog, muscle heaviness, and rapid heart rate drift

Clever marketing has led to thousands of people starting to use GLP-1 agonists with the hope of looking better on the beach next summer

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