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Verdict: Don't swap your sunscreen for supplements just yet

Bloating and constipation may respond less predictably to split dosing

In the SURMOUNT trials, hair loss affected around 5 percent (women 7.1 percent, men 0.5 percent)

This timeframe allows providers to assess: Side effect severity Appetite changes Energy levels Overall tolerance If side effects are present but mild, staying at the starting dose longer often leads to improvement without sacrificing progress