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Selenium: This mineral is a cofactor for the enzyme glutathione peroxidase

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Skin hydration, wrinkling, and elasticity were assessed at baseline and after 12 weeks, with adjustments for temperature, humidity, and ultraviolet A light exposure (using weather data during the evaluation intervals)

Research is mixed, and supplementing with DHEA can be risky,7 but some studies suggest potential short-term, minor benefits (like improved feelings of well-being) in certain populations, such as older women with reduced natural DHEA levels.8 Ultimately, more research is needed before it can be said if DHEA supplementation is safe, particularly in the long term