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JANUVIA should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis
Many reports showed that GLP-1 effects involve neural modulation and peripheral effects, which increase satiety, resting energy expenditure and lower plasma concentrations of free fatty acids [20]-[22]
The introduction of GLP-1 therapeutics has revolutionized the treatment of type 2 diabetes and obesity, with other potential indications under investigation
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