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32,33 Under physiological conditions, besides the paracrine secretion pathway in the gastrointestinal tract, most endogenous GLP-1 in circulation is locally deactivated by DPP-4 and the liver, 34 making it difficult to directly enter the CNS through the blood-brain barrier
Kim HI, Raffler J, Lu W, Lee J-J, Abbey D, Saleheen D, et al
Douros A, DellAniello S, Yu OHY, Filion KB, Azoulay L, Suissa S
These networks help platforms handle cases that need testing or physical review
Real-life experiences: GLP-1s in action As you read these real life stories, remember that GLP-1 use is not currently FDA approved for people with type 1 diabetes, and results may vary
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