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Typically, the RING domain of E3 ubiquitin ligase facilitates the attachment of K48-linked polyubiquitin chains to target proteins for subsequent proteasomal degradation 49,50

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ONLY MIX WITH STERILE BACTERIOSTATIC WATER The purity and sterility of bacteriostatic water are essential to prevent contamination and to preserve the shelf-life of dissolved peptides

PDS5B also acts synergistically with BRCA2-DSS1 to help overcome the interference of RPA in DNA strand exchange and works in conjunction with RAD51 to protect dsDNA against digestion by MRE11-RAD50-NBS1