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In addition, ATGL depletion significantly downregulated HSL and MGL levels in brown adipose tissue (BAT), while the total lipase activity in WAT was barely affected [53]
PPAR and C/EBP cooperatively promote differentiation and induction of several adipocyte-specific genes, including lipoprotein lipase (LPL), adipocyte protein 2 (aP2), fatty acid synthase (FAS), and perilipin in the terminal stage of differentiation (Figure 1)
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