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Parker, A
Filed Cancerization: Basic Science and Clinical Applications
Studies in Caco-2 cell monolayers (a cellular model of human intestinal epithelium) have shown that metformin is efficiently taken up across the apical (luminal-facing) surface of enterocytes via bidirectional transporters, but that efflux across the basolateral surface of enterocytes is limited, resulting in the accumulation of metformin in the epithelium [16], possibly accounting for the greatly increased metformin concentration seen in these cells
I have a doctors letter and prescription information if needed. Provide documentation when requested, but dont volunteer excessive medical details
Gallbladder disease : Semaglutide may increase the risk of cholelithiasis and cholecystitis
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