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doi: 10.1155/2019/7247238 17 YueCYangXLiJChenXZhaoXChenYet al

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Patients should not self-inject peptides without medical supervision

Intra-arterial delivery can increase early brain exposure but requires careful control of cell size, dose, infusion rate, and microvascular-occlusion risk [48]

METs cleave CXCL8 into active monomers to promote EMT and tumorendothelial adhesion and release matrix metalloproteinases (MMPs) to degrade ECM, facilitating metastasis