It has a substantial body of promising preclinical research, but that has not yet translated into robust clinical evidence in humans, says Nora Khaldi, PhD, a Dublin-based molecular scientist and founder of Nuritas, a biotechnology company that uses AI to analyze peptides from plant sources for human health and wellness purposes
This has spurred interest in microbiota-targeted interventions, including probiotics, prebiotics, and dietary modulation
But yeah, I mean, you hear that all the time that people inject something, and there was more in it than they thought
In addition to JPH-203, other drugs currently in preclinical and clinical trials targeting LAT1 include IPA-131, QBS-10072S, TLX101-CDx, 124I-ACD-101, 211At-TLX-102, OKY-034, [18F] NKO-028 (Table 1)
Wang et al., 2021