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Choo BKM, Kundap UP, Kumari Y, Hue S-M, Othman I, Shaikh MF
Key pathways studied include glucose-dependent insulin secretion from pancreatic beta-cells, glucagon suppression from alpha-cells, delayed gastric emptying, and hypothalamic appetite regulation
A new study found that over time, the majority of weight loss from GLP-1 medication was from fat loss, and not muscle loss
However, exposure to excessive heatsuch as direct sunlight, hot vehicles, or temperatures above 86Fcan accelerate degradation and reduce the medication's effectiveness
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