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The primary outcome of interest for the trial was percent change from baseline in body weight at 72 weeks

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Practical Implications of the Research If true in humans, semaglutide could transform the treatment of addiction

The European regulatory approval of afamelanotide (Scenesse) for erythropoietic protoporphyria (EPP) was supported by Phase 3 randomized controlled trials demonstrating significantly increased pain-free light exposure time in EPP patients validating MC1R-mediated photoprotection as a real biological effect

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